Hotels in Southern Indiana

your current months are December, 2024 and January, 2025.
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Where to stay in Southern Indiana?

Top neighborhoods in Southern Indiana

Louisville Science Center featuring outdoor art

West Main Historic District

Boasting the largest collection of cast iron façades outside New York's SoHo district, this historic area features "Museum Row" with attractions like the Louisville Slugger Museum and Muhammad Ali Center.

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West Main Historic District

Top landmarks in Southern Indiana

Louisville Slugger Museum showing interior views

Louisville Slugger Museum

Louisville Slugger Museum is just one of the attractions in Downtown Louisville, Louisville so you might want to stop by during your trip. Why not take a stroll along the riverfront and watch the sunset while you're here? If you want to experience more of the culture Louisville has to offer, head to Kentucky Bourbon Trail Visitor Center, Louisville Science Center, and 21c Museum Hotel.

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Louisville Slugger Museum

Learn more about Southern Indiana

Southern Indiana is applauded for its live music and entertainment with such cultural attractions as Indiana Railway Museum and Frazier International History Museum. The city has something for everyone including its casinos, restaurants, and sights like Patoka Lake and Hoosier National Forest.

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Kentucky Center for the Performing Arts featuring modern architecture

Frequently asked questions

What accommodations do travelers like in Southern Indiana?
The Destination B&B, Hilton Garden Inn Jeffersonville and The Pepin Mansion Historic B&B are all properties that our guests really like.
Can I book a refundable hotel in Southern Indiana?
If you want the flexibility to change your travel plans to Southern Indiana, most hotels provide refundable* bookable rates. You can find these accommodations by searching our site and using the “fully refundable” filter to narrow the results down.
Which Southern Indiana hotels do travelers like for their great location?
Our guests rave about the location of these properties: Galt House Hotel Trademark Collection by Wyndham, Omni Louisville Hotel and Holiday Inn Express & Suites Louisville Downtown, an IHG Hotel.
Where should I consider staying in Southern Indiana if I want a cheap accommodation?
Two inexpensive options worth considering are Holiday Inn Express & Suites Louisville Downtown, an IHG Hotel and Baymont by Wyndham Evansville East. You can browse more choices on our site, including 23 motels.
Where can I stay in Southern Indiana if I want a vacation home instead of a traditional hotel?
If you want a good alternative to a hotel, review our selection of 328 vacation homes. In addition, there are 185 apartments and 47 condos.
Why should I book my Southern Indiana hotel with Hotels.com?
There are plenty of reasons to book your Southern Indiana travel with us: our free cancellations on selected hotels* gives you the flexibility you’re looking for, and with One Key™, our rewards program, you will be able to earn and use OneKeyCash™** on all eligible bookings such as hotels, car rentals, flights, vacation rentals and more on Hotels.com, Expedia and Vrbo.